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COL2A1 Antibody (H-300) is a rabbit polyclonal IgG

  • COL2A1 Antibody (H-300) is a rabbit polyclonal IgG provided at 200 µg/ml
  • epitope corresponding to amino acids 873-1072 mapping near the C-terminus of Collagen α1 Type II of human origin
  • recommended for detection of Collagen α1 Type II, and to a lesser extent, Collagen α1 Type I of mouse, rat and human origin by WB, IP, IF IHC(P) and ELISA
  • See 8 citations for COL2A1 Antibody (H-300)

The extensive family of COL gene products (collagens) is composed of several chain types, including fibril-forming interstitial collagens (types I, II, III and V) and basement membrane collagens (type IV), each type containing multiple isoforms. Collagens are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue, such as tendons and cartilage. All collagens contain a triple helix domain and frequently show lateral self-association in order to form complex connective tissues. Several collagens also play a role in cell adhesion, important for maintaining normal tissue architecture and function. In cartilage, Collagen Type II constitutes the bulk of the fibril. Sensitization with Collagen Type II induces an erosive polyarthritis in rats, mice and higher primates which can resemble rheumatoid arthritis and relapsing polychrondritis.

Информация для заказа:

Область использования:Производство:Santa Cruz
Метод: 
Объем:200 мкг/мл 
Кат. номер:sc-28887
Цена (с НДС 20%): В корзину Добавить в корзину
Наименование: COL2A1 Antibody (H-300) is a rabbit polyclonal IgG.
Примечание: SQ Category: Primary Antibodies,
Species: m, r, h,
Host Origin: human,
Applications: WB, IP, IF, IHC(P), ELISA,
UNSPSC: 12352203,
datasheet
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