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NOS3 Antibody (A-9) is a mouse monoclonal IgG2a

• NOS3 Antibody (A-9) is a mouse monoclonal IgG_2a provided at 200 µg/ml
• specific for an epitope mapping between amino acids 1173-1202 at the C-terminus of NOS3 of human origin
• recommended for detection of NOS3 (ecNOS) of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
• See 1 citations for NOS3 Antibody (A-9)

Nitric oxide (NO) has a broad range of biological activities and has been implicated in signaling pathways in phylogenetically diverse species. Nitric oxide synthases (NOSs), the enzymes responsible for synthesis of NO, contain an N-terminal oxygenase domain and a C-terminal reductase domain. NOS activity requires homodimerization as well as three cosubstrates (L-arginine, NADPH and O2) and five cofactors or prosthetic groups (FAD, FMN, calmodulin, tetrahydrobiopterin and heme). Several distinct NOS isoforms have been described and been shown to represent the products of three distinct genes. These include two constitutive Ca2+/CaM-dependent forms of NOS, including NOS1 (also designated ncNOS) whose activity was first identified in neurons, and NOS3 (also designated ecNOS), first identified in endothelial cells. The inducible form of NOS, NOS2 (also designated iNOS), is Ca2+-independent and is expressed in a broad range of cell types.

Информация для заказа:

Область использования: Первичные антитела и конъюгаты	Производство:	Santa Cruz
	Метод:
	Объем:	200 мкг/мл
	Кат. номер:	sc-376751
Цена (с НДС 20%):		В корзину
Наименование: NOS3 Antibody (A-9) is a mouse monoclonal IgG2a. Примечание: SQ Category: Primary Antibodies, Species: m, r, h, Host Origin: human, Applications: WB, IP, IF, IHC(P), ELISA, UNSPSC: 12352203, datasheet