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E-Selectin Antibody (D-7) is a mouse monoclonal IgG2a

  • E-Selectin Antibody (D-7) is a mouse monoclonal IgG2a provided at 200 µg/ml
  • raised against amino acids 311-610 mapping at the C-terminus of E-Selectin of human origin
  • recommended for detection of E-Selectin of human origin by WB, IP, IF, IHC(P) and ELISA

Selectins, also designated CD62 antigens, comprise a family of carbohydrate- binding proteins involved in mediating cellular interactions with leukocytes. L-Selectin (also designated LECAM-1 or CD62L) is expressed on the majority of B and naive T cells and on most monocytes, neutrophils and eosinophils. L-Selectin interacts with specific carbohydrates expressed by activated endothelial cells. P-Selectin (also designated GMP-140 or CD62P), expressed on activated platelets and endothelial cells, and E-Selectin (also designated ELMA-1 or CD62E), expressed on endothelial cells, exhibit overlapping ligand specificities. E-Selectin is expressed by cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining.

Информация для заказа:

Область использования:Производство:Santa Cruz
Метод: 
Объем:200 мкг/мл 
Кат. номер:sc-137054
Цена (с НДС 20%): В корзину Добавить в корзину
Наименование: E-Selectin Antibody (D-7) is a mouse monoclonal IgG2a .
Примечание: SQ Category: Primary Antibodies,
Species: human,
Host Origin: human,
Applications: WB, IP, IF, IHC(P), ELISA,
UNSPSC: 12352203,
datasheet
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