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N-CoR (H-303) / N-CoR Antibody (H-303) is a rabbit polyclonal IgG

  • N-CoR Antibody (H-303) is a rabbit polyclonal IgG provided at 200 µg/ml
  • epitope corresponding to amino acids 1881-2183 mapping near the C-terminus of N-CoR of human origin
  • recommended for detection of N-CoR of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine and bovine
  • See 41 citations for N-CoR Antibody (H-303)

Retinoids are metabolites of vitamin A (retinol) and are believed to represent important signaling molecules during vertebrate development and tissue differentiation. Two families of retinoid receptors have been identified. Retinoic acid receptors (RARs), include RARå, RAR∫ and RAR©, each of which have a high affinity for all-trans retinoic acids and belong to the same class of nuclear transcription factors as thyroid hormone receptors, vitamin D3 receptor and ecdysone receptor. Two cofactors that function to repress transcription, designated SMRT and N-CoR, have been shown to associate with the thyroid receptor and RAR in their unliganded state and are released from them upon ligand binding. The carboxy termini of both proteins contain receptor interacting domains while their amino termini contain two previously undescribed repressor domains. SMRT (silencing mediator for RARs and TRs) is 1495 amino acids in length. N-CoR (nuclear receptor corepressor) is a protein 2453 amino acids in length.

Информация для заказа:

Область использования:Производство:Santa Cruz
Метод: 
Объем:200 мкг/мл 
Кат. номер:sc-8994
Цена (с НДС 20%): В корзину Добавить в корзину
N-CoR (H-303) / N-CoR Antibody (H-303) is a rabbit polyclonal IgG Наименование: N-CoR (H-303) / N-CoR Antibody (H-303) is a rabbit polyclonal IgG .
Примечание: SQ Category: Primary Antibodies,
Species: m, r, h,
Host Origin: human,
Applications: WB, IP, IF, ELISA,
UNSPSC: 12352203,
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